Latest WHO signal
Ebola disease caused by Bundibugyo virus - Democratic Republic of the Congo
The Bundibugyo virus disease (BVD) outbreak in the Democratic Republic of the Congo is intensifying, with sustained transmission and continued increases in reported cases and deaths. Initially confined to the Mongbwalu health zone in Ituri Province, over the last two months, the outbreak has expanded to five provinces (Ituri, North Kivu, South Kivu, Haut-Uélé and Tshopo), now affecting 49 health zones. The outbreak is now the largest Ebola outbreak ever reported in the Democratic Republic of the Congo. As of 30 July 2026, a total of 3605 confirmed cases, including 1587 deaths, have been reported, corresponding to a crude case fatality ratio (CFR) of 44%. The continued increase in cases, expanding geographic spread, and persistently high mortality underscore the rapidly evolving nature of this public health emergency. During the most recent complete reporting week (epidemiological week 30), the highest weekly number of reported cases (567) and deaths (296) to date were recorded, underscoring the exceptional pace of transmission. The convergence of insecurity, population displacement and mobility, and cross-border movements complicate response operations and increase the risk of further geographical spread. National authorities in the Democratic Republic of the Congo, in collaboration with WHO and partners, continue to implement extensive response measures, however, a substantial scaling up of response activities is needed to get ahead of the outbreak. A regional preparedness and prioritization framework continues to guide readiness and response activities across the African Region. The confirmed BVD case reported in France on 24 June 2026 following deployment to support the outbreak in the Democratic Republic of the Congo recovered and was discharged on 4 July 2026 after two consecutive negative PCR test results. No secondary transmission has been identified, and all five flight contacts, as well as those listed in the Democratic Republic of the Congo completed their 21-day follow-up without developing symptoms. As of 1 August 2026, France has not reported any additional confirmed BVD cases for 28 days since the patient's discharge. On 28 July, the Ministry of Health of Uganda declared the end of the BVD outbreak in the country, following 42 days without a new confirmed locally transmitted case after the last confirmed case was discharged from care on 16 June 2026. The most recent imported case was discharged from a treatment centre on 16 July after two negative tests results. Following international guidance WHO will be monitoring the situation for 42 days from this date to ensure no chains of transmission have been missed. Uganda remains at risk of imported cases and re-introduction of BVD, due to ongoing transmission in neighbouring Democratic Republic of the Congo. WHO reiterates the need to maintain heightened surveillance, preparedness and control measures, particularly in view of continued population movement and the risk of cross-border transmission.
On 6 June 2026, WHO reassessed the risk of the outbreak of BVD to incorporate newly available information and align with the WHO Temporary Recommendations . The risk for countries sharing land borders with countries with documented Bundibugyo virus detection, the Democratic Republic of the Congo and Uganda at the time of assessment, was separated from the risk for other countries in the African Region. The risk in the Democratic Republic of the Congo was assessed as very high due to ongoing transmission and the co...
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Ebola disease caused by Bundibugyo virus - Democratic Republic of the Congo
high attentionThe Bundibugyo virus disease (BVD) outbreak in the Democratic Republic of the Congo is intensifying, with sustained transmission and continued increases in reported cases and deaths. Initially confined to the Mongbwalu health zone in Ituri Province, over the last two months, the...
WHO sourceEbola disease caused by Bundibugyo virus, Democratic Republic of the Congo & Uganda
high attentionThe Bundibugyo virus disease (BVD) outbreak in the Democratic Republic of the Congo remains active, with sustained transmission driving increases in reported cases and deaths. As of 15 July 2026, a cumulative total of 2124 confirmed cases, including 828 deaths, have been reporte...
WHO sourceEbola disease caused by Bundibugyo virus, Democratic Republic of the Congo & Uganda
high attentionThe Bundibugyo virus disease (BVD) outbreak in the Democratic Republic of the Congo continues to evolve rapidly, with sustained transmission and increasing numbers of reported cases. As of 1 July, a cumulative of 1460 confirmed cases, including 452 deaths, have been reported fro...
WHO sourceHantavirus outbreak linked to cruise ship travel, Multi-locations
elevated watchThis is the fifth Disease Outbreak News posting on the Andes hantavirus (ANDV) outbreak linked to the cruise ship M/V Hondius. The outbreak identification followed the notification to the World Health Organization (WHO) on 2 May 2026 of severe acute respiratory illness cases onb...
WHO sourceNipah virus disease - India
elevated watchOn 11 June 2026, the Kerala State Health Department confirmed one laboratory confirmed case of Nipah virus (NiV) infection in Kozhikode district, Kerala State, India. The case is an adult male who developed symptoms on 30 May 2026 and was hospitalized on 10 June 2026. He present...
WHO sourceYellow fever - Global
elevated watchYellow fever is a viral disease found in areas of Africa and the Americas, spread by infected mosquitoes. Following an increase of cases in the Americas in 2025, transmission activity remained into 2026. From 1 January to 26 May 2026, six countries reported a total of 79 human i...
WHO sourceEbola disease caused by Bundibugyo virus, Democratic Republic of the Congo & Uganda
high attentionThe Bundibugyo virus disease (BVD) outbreak in the Democratic Republic of the Congo continues to evolve rapidly, with sustained transmission and increasing numbers of reported cases. As of 17 June, a cumulative of 896 confirmed cases, including 232 deaths, have been reported fro...
WHO sourceEbola disease caused by Bundibugyo virus, Democratic Republic of the Congo & Uganda
high attentionThe Bundibugyo virus disease (BVD) outbreak in the Democratic Republic of the Congo continues to evolve rapidly, with increasing case numbers and geographic spread. As of 10 June, a cumulative of 676 confirmed cases, including 136 deaths, have been reported from the Democratic R...
WHO sourceEbola disease caused by Bundibugyo virus, Democratic Republic of the Congo & Uganda
high attentionThe Bundibugyo virus disease (BVD) outbreak in the Democratic Republic of the Congo continues to evolve rapidly, with increasing case numbers, geographic spread, and cross-border transmission to Uganda. As of 6 June, a total of 515 confirmed cases, with 91 deaths among these con...
WHO sourceEbola disease caused by Bundibugyo virus, Democratic Republic of the Congo & Uganda
watchThe Bundibugyo virus disease (BVD) outbreak in the Democratic Republic of the Congo and Uganda continues to evolve rapidly, with increasing case numbers, geographic spread, and ongoing cross-border transmission. As of 27 May, a total of 906 suspected cases and 223 deaths among s...
WHO sourceHantavirus outbreak linked to cruise ship travel, Multi-locations
elevated watchThis is the fourth Disease Outbreak News report on the Andes hantavirus outbreak linked to cruise ship travel, following the notification to the World Health Organization (WHO) on 2 May 2026 of severe respiratory illness cases aboard M/V Hondius, a cruise ship. Since the last DO...
WHO sourceEbola disease caused by Bundibugyo virus – Democratic Republic of the Congo
high attentionOn 15 May 2026, the Ministry of Public Health, Hygiene and Social Welfare, Democratic Republic of the Congo (DRC), and the Ministry of Health of Uganda declared an outbreak of Ebola Disease following the confirmation of Bundibugyo virus disease (BVD) in both countries. On 17 May...
WHO sourceEbola disease caused by Bundibugyo virus, Democratic Republic of the Congo & Uganda
high attentionOn 5 May 2026, the World Health Organization (WHO) was alerted of a high-mortality outbreak of unknown illness in Mongbwalu Health Zone, Ituri Province, Democratic Republic of the Congo (DRC), including deaths among health workers. On 14 May 2026, the Institut national de recher...
WHO sourceHantavirus cluster linked to cruise ship travel, Multi-country
high attentionThis is the third Disease Outbreak News report on the hantavirus cluster, following the notification to the World Health Organization (WHO) on 2 May 2026 of severe respiratory illness cases aboard MV Hondius, a cruise ship. Since the last DON was published on 8 May, two addition...
WHO sourceHantavirus cluster linked to cruise ship travel, Multi-country
high attentionOn 2 May 2026, a cluster of passengers with severe respiratory illness aboard a cruise ship was reported to the World Health Organization (WHO). At that time, according to the ship operator, 147 passengers and crew were onboard, and 34 passengers and crew had previously disembar...
WHO sourceHantavirus cluster linked to cruise ship travel, Multi-country
high attentionOn 2 May 2026, a cluster of passengers with severe respiratory illness aboard a cruise ship was reported to the World Health Organization. The ship is carrying 147 passengers and crew. As of 4 May 2026, seven cases (two laboratory confirmed cases of hantavirus and five suspected...
WHO sourceMeasles - Bangladesh
high attentionOn 4 April 2026, the National International Health Regulations (IHR) Focal Point for Bangladesh notified WHO of a nationwide increase in measles cases, geographically affecting 58 out of 64 districts across all eight divisions in Bangladesh. A total of 19 161 suspected measles c...
WHO sourceAvian Influenza A(H9N2) - Italy
elevated watchOn 21 March 2026, the National International Health Regulations (IHR) Focal Point for Italy notified the World Health Organization (WHO) of the identification of a human case of avian influenza A(H9) in an adult male returning from Senegal. Next generation sequencing confirmed I...
WHO sourceInternational food safety event: Infant formula and products containing arachidonic acid oil contaminated with cereulide toxin - Multi-country
elevated watchMulti-country recalls of infant formula and other products have been initiated after cereulide toxin, was detected in batches of multiple internationally distributed brands. Investigations have identified arachidonic acid (ARA) oil, used as an ingredient in the implicated produc...
WHO sourceMpox: recombinant virus with genomic elements of clades Ib and IIb – Global situation
elevated watchRecombination of monkeypox virus (MPXV) strains has been documented in recent months, with two cases of a recombinant strain comprising clade Ib and IIb MPXV reported. Recombination is a known natural process that can occur when two related viruses infecting the same individual...
WHO sourceNipah virus infection - Bangladesh
elevated watchOn 3 February 2026, the International Health Regulations National Focal Point (IHR NFP) for Bangladesh notified WHO of one confirmed case of Nipah virus (NiV) infection in Rajshahi Division. The patient developed fever and neurological symptoms on 21 January. Nipah virus infecti...
WHO sourceNipah virus disease - India
watchOn 26 January 2026, the National IHR Focal Point for India notified WHO of two laboratory‑confirmed cases of Nipah virus (NiV) infection in West Bengal State. Both are healthcare workers at the same private hospital in Barasat (North 24 Parganas district). NiV infection was conf...
WHO sourceMarburg virus disease- Ethiopia
elevated watchOn 26 January 2026, the Ministry of Health of Ethiopia declared the end of the Marburg virus disease (MVD) outbreak. This declaration came after two consecutive incubation periods (a total of 42 days) since the last person confirmed with MVD died and was given a safe and dignifi...
WHO sourceMiddle East respiratory syndrome coronavirus - Global update
high attentionSince the beginning of 2025 and as of 21 December 2025, a total of 19 cases of Middle East respiratory syndrome coronavirus (MERS- CoV), including four deaths have been reported to WHO globally. Of the 19 cases, 17 were reported by the Kingdom of Saudi Arabia (KSA), and two were...
WHO sourceSeasonal influenza - Global situation
high attentionSeasonal influenza (‘the flu’) is an acute respiratory infection caused by influenza viruses that circulate globally and year-round. It can cause illness ranging from mild to severe, sometimes resulting in hospitalization or death. Seasonal influenza activity has increased globa...
WHO sourceBroader transmission of mpox due to clade Ib MPXV – Global situation
high attentionThe purpose of this report is to raise awareness about the local transmission of clade Ib monkeypox virus (MPXV) among men who have sex with men (MSM) in countries previously unaffected or to date reporting only cases linked to travel. This report summarizes recent epidemiologic...
WHO sourceAvian Influenza A(H5N5)- United States of America
elevated watchOn 15 November 2025, WHO was notified of the 71st confirmed human case with influenza A(H5) since early 2024 in the United States of America— the first human case reported in the United States of America since February 2025. On 20 November, U.S. Centers for Disease Control and P...
WHO sourceEbola virus disease – Democratic Republic of the Congo
elevated watchOn 1 December 2025, the Ministry of Health (MoH) of the Democratic Republic of the Congo (DRC) declared the end of the Ebola virus disease (EVD) outbreak which had been declared on 4 September 2025. The end was declared after two consecutive incubation periods (a total of 42 day...
WHO sourceDiphtheria - African Region (AFRO)
high attentionFrom 1 January to 2 November 2025, a total of 20 412 suspected diphtheria cases, including 1 252 deaths (an average case fatality ratio [CFR] - 6 %) have been reported across eight Member States in the WHO African Region (Algeria, Chad, Guinea, Mali, Mauritania, Niger, Nigeria,...
WHO sourceMarburg virus disease- Ethiopia
high attentionOn 12 November 2025, WHO noted a press release from the Ethiopian Ministry of Health (MoH), and the Ethiopian Public Health Institute (EPHI), announcing suspected viral hemorrhagic viral fever (VHF) in Jinka town, South Ethiopia Regional State, Ethiopia. On 14 November 2025, the...
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